Alexis obtained his PhD degree in faculty of sciences, Austral University, Valdivia, Chile. During his PhD research, he studied the role of the proteasome system and autophagy in the degradation and proteolityc processing of amyloid precursor protein (APP). In November 2017 Alexis joined the laboratory of Prof. Dikic as a Postdoctoral researcher investigating how phosphoribosyl-linked serine ubiquitination affects cellular functions.