We are thrilled to welcome our new Leica STELLARIS FALCON confocal laser-scanning microscope with integrated fluorescence lifetime imaging (FLIM) to our institute and are eager to begin exploring its full potential for our research.
This state-of-the-art imaging platform will significantly enhance imaging-based research in biochemistry, molecular biology and biomedicine. It combines a flexible white light laser with highly sensitive hybrid detectors and advanced FLIM capabilities, enabling fast, high-resolution and quantitative imaging in living cells. The system supports sophisticated applications such as FRET-based measurements and functional imaging based on fluorescence lifetimes.
 

Using the new STELLARIS FALCON microscope, we and contributing researchers, aim to dissect dynamic mechanisms of cellular quality control and autophagy, decode immune signalling pathways in inflammation and cancer, and visualise RNA- and DNA-driven processes in tumorigenesis, viral infection and cellular stress responses in real time. These approaches will generate new mechanistic insights into fundamental biological processes and disease-relevant pathways and, in the longer term, accelerate the translation of basic discoveries into innovative therapeutic strategies.
The acquisition of this microscope is co-funded by the DFG FUGG programme and the European Union through the European Regional Development Fund (EFRE) and contributes directly to strengthening research excellence, innovation capacity and regional development in Hessen.