Seminars in Biochemistry

2016

 

28.09.16 Robert Ernst,
BMLS - Goethe University Frankfurt, Germany
"A new hope in functional genomics: genetic screens with CRISPR technology"

 

28.09.16 Robert Ernst,
BMLS - Goethe University Frankfurt, Germany
"Eukaryotic sensors for membrane compositions - importance of intra-membrane sensing"

 

14.09.16 Holger Richly,
Institute of Molecular Biology gGmbH (IMB), Mainz, Germany
"Late-life inhibition of key autophagy genes extends C.elegans lifespan"

 

08.06.16 Thordur Oskarsson,
Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), German Cancer Research Center (DKFZ), Heidelberg, Germany
"Extracellular matrix proteins of stem cell niches: role in breast cancer metastasis"

 

25.05.16 Nirmal Robinson,
CECAD Research Center, University of Cologne, Cologne, Germany
"Metabolic Regulation of Cell Autonomous Immune defense against S. Typhimurium"

 

18.05.16 Andrea Pichler,
Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
"Sumo Rules"

 

13.05.16 Brian Caudill,
Integrated DNA Technologies, BVBA, Leuven, Belgium
"Building new tools for more potent CRISPR-Cas9 Genome Editing"

 

27.04.16 Boris Pfander,
Max-Planck Institute of Biochemistry, Martinsried, Germany
"How to prevent and deal with replication stress"

 

09.03.16 Carmine Settembre,
Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy
"Roles and regulators of autophagy during skeletal growth"

 

02.03.16 Wilfried Roth,
Institute for Pathology Johannes Gutenberg-Universität Mainz Germany
"Pathology of cell death"
(Taking place at the Georg-Speyer-Haus)

 

09.02.16 Shravan Kumar Mishra,
Indian Institute of Science Education and Research (IISER) Mohali, India
"Ubiquitin- like processing generates an intron-specific RNA splicing factor"

 

2015

 

Mini-symposium on Autophagy

28.10.15 Patrice Codogno,
Institut Necker Enfants-Malades, INSERM U1151-CNRS UMR 8253, Paris, France.
"Autophagy and primary cilia in stress response"

28.10.15 Nicholas Ktistakis,
Signalling Department, Babraham Institute, Cambridge, UK.
"Starvation-induced and selective autophagy: the first 3 minutes"

 

 

15.10.15 Lilliana Radoshevich,
Institut Pasteur Paris, France
"ISG15 counteracts Listeria monocytogenes infection"

 

28.09.15 Hind Medyouf,
Georg-Speyer-Haus Institute for Tumor Biology, Frankfurt, Germany
"Clonal Heterogeneity and Niche Dependency in Human Myelodysplasia"

 

16.09.15 Eric Fischer + Bennett,
Eric Fisher: Cancer Biology, Dana-Farber Cancer Institute & BCMP, Harvard Medical School
"Subversion of host cell function by Chlamydia"

Eric Bennet: Division of Biological Sciences, University of California-San Diego (UCSD)
"Ubiquitin-dependent control mechanisms that govern protein homeostasis"

 

14.09.15 Hagai Abeliovich,
Robert H. Smith Faculty of Agriculture, Food and Environment Hebrew University of Jerusalem, Israel
"Mitochondrial autophagy: How do cells select what to degrade?"

 

20.07.15 Thomas Rudel,
Chinese Academy of Sciences, Institute of Biochemistry and Cell Biology, Shanghai, China.
"A Kinase Initiated Death Pathway"

 

27.05.15 Liming Sun,
Biozentrum der Universität Würzburg, Department of Microbiology, Würzburg, Germany
"Subversion of host cell function by Chlamydia"

 

20.05.15 Huib Ovaa,
NKI Amsterdam, Netherlands.
"Development and use of ubiquitin-based reagents"

 

13.05.15 Hannelore Ehrenreich,
Clinical Neuroscience Max Planck Institute for Experimental Medicine Göttingen, Germany.
"Autism: A disease of the synapse – search for mechanistic insight"

 

29.04.15 Sascha Martens,
Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.
"Molecular Mechanisms of Selective Autophagy"

 

25.03.15 Anton Wellstein,
Georgetown University Medical School, Lombardi Comprehensive Cancer Center, Washington DC, USA.
"The Hippo pathway in cancer malignant progression"

 

24.03.15 Tilmann Bürckstümmer,
Horizon Genomics GmbH Campus Vienna Biocenter Vienna, Austria.
"An efficient pipeline for CRISPR/Cas-mediated genome engineering in haploid human cells"

 

26.02.15 Daniel Abankwa,
Turku Centre for Biotechnology University of Turku and Abo Akademi University BioCity, Turku, Finland.
"Targeting the nanoscale signaling architecture of Ras in cancer and cancer stem cells"

 

11.02.15 Naoko Mizuno,
Max Planck Institute of Biochemistry, Martinsried, Germany.
"Structural basis for the extended CAP-Gly domains of p150 binding to microtubules and its implication for tubulin dynamics"

 

28.01.15 Alexander Höllein,
Technische Universität München, Germany
"Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma - mechanistic insights"

 

21.01.15 Henning Urlaub,
Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
"The potential of mass-spectrometric proteomics for cell biological and biomedical research"

 

2014

 

12.12.14 Manuel Kaulich,
Dept. Cellular & Molecular Medicine, UCSD - School of Medicine, La Jolla, USA.
"Determining G1 Restriction Point Control by Gene-Editing and Single-Cell Analysis" <

 

03.11.14 James Olzman,
Seminar in Biochemistry.
University of California, Berkeley Nutritional Science & Technology Berkeley, CA, USA
"At the intersection of ER protein quality control and lipid droplets" <

 

08.10.14 Maja Köhn,
EMBL Heidelberg, Genome Biology Unit Heidelberg, Germany.
"Chemical activation of protein phosphatase-1 as a tool to study its roles in health and disease" <

 

25.06.14 Michael Hensel,
Department for Microbiology university Osnabrück.
"The intracellular lifestyle of Salmonella enterica: a new view on manipulations of the endosomal system" <

 

13.06.14 Martin Scheffner,
Seminar in Biochemistry.
"The ubiquitin ligase E6AP and its role in human disease" <

 

04.06.14 Carsten Sachse,
Seminar in Biochemistry.
"Cryo-EM studies of autophagy receptor p62 – towards a mechanism of selective autophagy"" <

 

07.05.14 Hemmo Meyer,
Seminar in Biochemistry.
"The ubiquitin-dependent segregase VCP/p97 governs endosomal sorting and autophagy" <

 

23.04.14 Rajesh Gokhale,
Seminar in Biochemistry.
"Enantiostasis Rewiring of Cellular Networks in Depigmenting Disorder Vitiligo" <

 

26.02.14 Christian Ungermann,
University of Osnabrück.
"Novel functions of the yeast Rab7 GTPase in lysosome/vacuole biogenesis" <

 

19.02.14 Sebastian Wagner,
Medizinische Klinik II, Goethe University Frankfurt.
"Decoding Ubiquitin signals by quantitative mass spectrometry" <

 

20.01.14 Zvulun Elazar,
Department of Biological Chemistry The Weizmann Institute of Science Rehovot, Israel.
"Atg8 family members and early stages of autophagosome formation" <

 

2013

 

11.12.13 Simon Wilkinson,
To be announced.

 

27.11.13 Fulvio Reggiori,
Department of Cell Biology, Cell Microscopy Centre and Institute of Biomembranes, University Medical Center Utrecht
"Coronaviruses hijack LC3-I positive EDEMosome membranes for replication."

 

22.11.13 Thomas Sommer,
Max-Delbrück-Center for Molecular Medicine and Humboldt-University zu Berlin.
"Protein Export from the Endoplasmic Reticulum involves a channel formed by Der1"

 

07.11.13 David Toczyski,
Department of Biochemistry and Biophysics University of California, San Francisco USA.
"to be announced"

 

18.09.13 Karin Kühnel,
Department of Neurobiology MPI for Biophysical Chemistry Göttingen, Germany.
"Structural and functional characterization of PROPPINs"

 

03.07.13 Thomas Wollert,
MPI of Biochemistry, Martinsried. Germany
"A coat that fits all sizes: Molecular mechanism of autophagosome biogenesis"

 

21.06.13 Anindya Dutta,
Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA
"HRe-replication and microDNAs, two types of genomic instability in normal and cancer cells"

 

11.06.13 Sharad Kumar,
Centre for Cancer Biology, SA Pathology, Adelaide, Australia
"Nedd4 family of ubiquitin ligases in physiology and disease"

 

05.06.13 Franz Herzog,
Gene Center Ludwig-Maximilians-Universität München, Germany
"Identifying Missing Links in Structrual Biology and Interaction Proteomics"

 

22.05.13 Varatharajan Sundaramurthy,
Max-Planck-Istitute of Cell Biology, Dresden, Germany
"An integrative approach to identify and exploit crucial host determinants of intracellular bacterial survival"

 

21.05.13 Mike Matunis,
Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
"SUMOylation and Control of Progression through Mitosis"

 

25.02.13 Attila Remenyi,
Department of Biochemistry, Eotvos Lorand University, Budapest, Hungary
"Protein-protein interactions that give sense to MAPK signalling"

 

2012

 

20.02.2012 Shravan Kumar Mishra,
Department of Molecular Cell Biology Max Planck Institute of Biochemistry Martinsried
"Ubiquitin-like modifiers and regulation of RNA splicing"

 

09.03.2012 Christian Kubisch,
Institute of Human Genetics University of Ulm
"Human Genetics as a means to identify novel disease-associated genes and to elucidate gene function"

 

21.11.12 Jörg Höhfeld,
Institute for Cell Biology, University Bonn
"Cellular mechanotransduction relies on tension-induced und chaperone-assisted autophagy"

 

17.11.12 Konstanze Winkelhofer,
Ludwig-Maximilians-University Munich

 

08.10.12 Yaron Galanty,
Gurdon Institut, University of Cambridge

 

25.09.2012 Caudio Joazeiro,
Department of Cell Biology The Scripps Research Institute La Jolla, CA, USA
"The E3 Ligase Listerin/Ltn1 is implicated in neurodegeneration and mediates a novel pathway of protein quality control."

 

18.09.12 Brenda Schulman,
Howard Hughes Medical Institute, St. Jude Children's Research Hospital
"Twists and turns in ubiquitin conjugation cascades"

 

2011

 

10.03.2011 Sarit Larisch,
Biology Department, University of Haifa, Mount Carmel, Haifa, Israel
"The ARTS connection; Apoptosis, Mitochondria and Tumor suppression"

 

15.03.2011 John Silke,
Department of Biochemistry, La Trobe University, Victoria, Australia
"The regulation of TNF signalling and Immunity by IAPs"

 

21.03.2011 Fraser Coxon,
Department for Medicine & Therapeutics, Institute of Medical Sciences, University of Aberdeen, UK
"Insights into osteoclast cell biology from studies of the bone disease osteopetrosis"

 

25.03.2011 Margaret Frame,
Edinburgh Cancer Research Centre, Edinburgh, UK
"Adhesion signalling in cancer processes"

 

05.10.2011 Alexander Buchberger,
Theodor-Boveri-Institut, Universität Würzburg, Germany
"The AAA ATPase Cdc48/p97 and its cofactors"

 

2010 & Before

 

20.01.2010 Matthias Peter,
ETH Zürich, Swizerland

 

22.01.2010 Arne Östman,
Cancer Center Karolinska, Karolinska Institutet, Sweden
"Cancer-associated fibroblasts; a source of novel candidate biomarkers and drug targets"

 

01.02.2010 Henning Walczak,
Imperial College London, Hammersmith Hospital, London, UK<br />
&quot;The importance of linear ubiquitination at the apex of the TNF
signal transduction cascade&quot;

 

03.03.2010 Ernst Stelzer,
European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
"Light sheet based fluorescence microscopes (LSFM, SPIM, DSLM) reduce phototoxic effects by several orders of magnitude"

 

24.03.2010 Marcus Krüger,
Max-Planck-Institute for Heart and Lung Research Department of cardiac Development and Remodeling, Bad Nauheim, Germany

 

02.06.2010 Dirk Bumann,
Biozentrum, University Basel, Switzerland
"System-level analysis of Salmonella / host interactions during infection"

 

16.06.2010 Hermann Steller,
Howard Hughes Medical Institute, The Rockefeller University, New York, USA
"Death by Degradation: Regulation of apoptosis by the ubiquitin-proteasome system“

 

31.08.2010 Wade Harper,
IBC II and FMLS Lecutre
Department of Pathology, Harvard Medical School, Boston, MA, USA
"Proteomic and Genetic analysis of the Ubiquitin system"
This seminar takes place in building 22 lecture hall 2 at 17.00 h.

 

27.09.2010 Zvulun Elazar,
Department of Biological Chemistry The Weizmann Institute of Science, Rehovot, Israel
"Mechanism of autophagosomes biogenesis"

 

06.10.2010 Jonathan Howard,
Institute for Genetics, University Cologne, Cologne
"Cell biology of a novel resistance mechanism in the mouse against the protozoan parasite, oxoplasma gondii: something for Everybody"

 

22.10.2010 Michael Rape,
Department of Molecular and Cell Biology, University of California at Berkeley, USA
"Function and assembly of K11-linked ubiquitin chains "

 

28.10.2010 Gudula Schmidt,
Institute for Experimental and Clinical Pharmacology and Toxicology
University of Freiburg
"Molecular strategies of pathogenic bacteria – toxins control Rho GTPases"

 

28.01.2009  Benno Jungblut,
PhD, MPI für Herz und Lungenforschung
"Genetic Control of Cell Behavior during Zebrafish Heart Morphogenesis"

 

10.02.2009 Pascale COSSARD
, Institut Pasteur, Paris, France
“The Bacterial Pathogen Listeria monocytogenes: the Rise of a Mutifacted Model”

 

12.03.2009 Elizabeth BLACKBURN
University of California San Francisco, USA
Title pending,

 

20.03.2009 Susumu TONEGAWA
Massachusetts Institute of Technology, Cambridge, USA
“Neural Mechanisms for Memory”

 

24.03.2009  Wade Harper,
Frankfurt Ubiquitin meeting 2009 :
Regulation of the proteasome via uiquitin chain dynamics
Dan Finley, Integrating proteomic and RNAi studies identifies new modules in ubiquitin and checkpoint signaling
Both from Harvard University Boston, USA

 

01.04.2009 Soichi Wakatsuki,
Structural Biology Research Center Institute of Materials Structure Science Photon Factory, KEK, Japan
"Structural insights into ubiquitin recognition in vesicle transport and signal transduction: ESCRT pathway and Finding NEMO"

 

29.04.2009 Nathan Brady
German Cancer Research Center (DKFZ) Heidelberg, Germany
"Resolving the connections between apoptosis and autophagy: molecular cell biology meets systems biology"

 

20.05.2009 Boris Macek
Proteome Center Interfaculty Institute for Cell Biology University of Tübingen, Germany
"Quantitative proteomics in the analysis of biological signal transduction"

 

03.06.2009 Felix Randow
MRC Laboratory of Molecular Biology, Cambridge UK
"IKK family kinases in innate immunity: their regulation by adaptor proteins and ubiquitin"

 

10.06.2009 Wim van Hul
Medical and Veterinary Sciences University Antwerpen, Belgium
"The molecular genetics of too much bone"

 

17.06.2009 Alain Israël
Cell signaling and activation Institut Pasteur, France
"Regulation of the NF-kB signaling cascade"

 

23.06.2009 Venki RAMAKRISHNAN
MRC Laboratory of Molecular Biology, Cambridge, UK
“Induced fit: A common strategy used by the Ribosome”

 

06.07.2009 Benjamin G. Neel
Ontario Cancer Institute, Toronto, Canada
"The Ras/Map kinase syndromes"

 

08.07.2009 Ariel Stanhill
Department of Biochemistry Technion, Faculty of Medicine Haifa, Israel
"Mechanisms of proteasome adaptation to protein misfolding"

 

16.09.2009 Matthias Husmann
, Institut für Medizinische Mikrobiologie und Hygiene, Johannes Gutenberg Universität Mainz
"Influential circles: pore forming toxins challenge cellular self-defense"

 

21.09.2009 Kazuhiro Iwai
Department of Biophysics and Biochemistry, Graduate School of Medicine, Osaka University,
„Linear Polyubiquitination: A newly identified regulator Involved of NF-kB signalling"

 

17.11.2009 Philip COHEN
Scottish Institute for Cell Signalling College of Life Science, University of Dundee, UK

 

04.12.2009 Nancy Hynes
Friedrich Miescher Institute for Biomedical Research (FMI) Basel, Switzerland
"Targeting molecular alterations in breast cancer"

 

09.12.2009 Richard Marais
CR UK Centre for Cell and Molecular Biology The Institute of Cancer Research, London, UK
"RAF and RAS signalling in melanoma: biology and therapeutics"

 

16.12.2009 Joern Dengjel
FRIAS-LIFENET, Universität Freiburg, Germany
"Spatio-temporal protein dynamics during autophagy"

 

18.12.2009 Christian Behrends,
Department of Pathology, Harvard Medical School, Boston, USA
"Network organization of the human autophagy system"

 

22.01.2008 Josef Penninger,
Institte of Molecular Biotechnology GmbH, Vienna, Austria
 "From Systems Genetics in Flies to human Medicine"

 

14.03.2008 Tim Mosmann,
Center for Vaccine Biology and Immunology, University of Rochester Medical Center, USA "Title pendingl"

 

30.04.2008 Thomas Sommer,
Max-Delbrück-Center for Molecular Medicine, Berlin
"The HRD Ubiquitin Ligase and Protein Quality Control in the Secretory Pathway"

 

14.05.2008 >Manolis Pasparakis,
Institute for Genetics, University of Cologne
"IKK/NF-*B signaling in inflammation and cancer"

 

19.05.2008 Patrick Matthias, Friedrich Miescher,
Institute for Biochemical Research (FMI), Basel, Switzerland
"Analysis of Histone deacetylase function in the lymphoid system and beyond"

 

23.05.2008 Yosef Yarden Weizmann,
Institute of Science, Israel
"EGFR and HER2: an oncogenic alliance and targets for cancer therapies"

 

12.07.2008 Kanti Bhoola,
University Perth, Australia
"Epigenetics and Cancer"

 

12.08.2008 Oliver Anderka,
Sanofi-Aventis Deutschland, Frankfurt
"Biophysical characterization of protein-compound and protein-protein interactions"

 

12.08.2008 Tony Pawson,
Samuel Lunenfeld Research Institute, Mt Sinai Hospital, University of Toronto, Canada  "SH2 domains and tyrosine kinases - back to the future"

 

05.11.2008 Tony Pawson,
Samuel Lunenfeld Research Institute, Mt Sinai Hospital, University of Toronto, Canada
 "SH2 domains and tyrosine kinases - back to the future"

 

18.11.2008 Peter Walter,
University of California, San Francisco, USA
 "Protein Homeostasis in Health and Disease"

 

25.11.2008 Edward A. Dennis,
University of California, San Diego, USA
 "Eicosanoid Lipidomics and Phospholipase A2 Role in Inflammatory Disease"

 

05.12.2008 Dr. Vishva Dixit,
Physiological Chemistry, Genentech
"Ubiquitin editing"