Seminars in Biochemistry
(cancelled) March 16th, 2020 Carsten Janke
"The Tubulin Code – a mechanism to control the microtubule cytoskeleton"
January 29th, 2020 Mario Looso
Max Planck Institute for Heart and Lung Research,
Bad Nauheim, Germany
"Beyond accessibility: ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation"
January 22nd, 2020 Thorsten Hoppe
Professor at the Faculty of Mathematics and Natural Sciences/Department of Biology
Institute for Genetics and CECAD Cologne,
University of Cologne, Germany
"Organismal Regulation of Ubiquitin-Mediated Quality Control"
November 13th, 2019 Malavika Raman
Tufts University School of Medicine
Department of Developmental, Molecular and Chemical Biology
"Tête-à-tête: The p97-UBXD8 complex regulates ER-mitochondrial contact sites"
October 23th, 2019 Marcel Schulz
Max-Planck-Institut für Informatik
High-throughput Genomics & Systems Biology
"Understanding transcriptional regulation from large-scale epigenomics data"
July 10th, 2019 Konstanze Winklhofer
Institute for Biochemistry and Pathobiochemistry
"A Role of Linear Ubiquitination in Protein Quality Control: Implications for Neurodegenerative Diseases"
December 10th, 2018 Markus Diefenbacher (CANCELED)
Department of Biochemistry and Molecular Biology University of Würzburg, Germany
"Targeting deregulated protein stability in lung and colorectal cancer"
December 04th, 2018 Konstanze Winklhofer (Seminar in Biochemistry & SFB1177 seminar)
Institute for Biochemistry and Pathobiochemistry, Ruhr-University, Bochum, Germany
"A Role of Linear Ubiquitination in Protein Quality Control: Implications for Neurodegenerative Diseases"
November 01th, 2018 Aditya Murthy
Genentech Inc., Department of Cancer Immunotherapy and Hematology, South San Francisco, CA, USA
"Leveraging mass spectrometry and genome editing to study innate immunity"
September 21th, 2018 Luke Wiseman
Associate Professor, Dept. of Molecular Medicine, The Scripps Research Institute MEM220, La Jolla, California
"Unexpected Outcomes: Non-secretory functions of the Unfolded Protein Response"
June 22th, 2018 Marco Hein
Department of Cellular Molecular Pharmacology, University of California, San Francisco, USA
"Dissecting cytomegalovirus infection using CRISPRi/n and single-cell transcriptomics"
March 16th, 2018 Aitor Hierro
CIC bioGUNE, Derio, Spain
February 28th, 2018 Alexandra Trifunovic
CECAD Research Center, University of Cologne, Germany
"Mammalian mitochondrial unfolded protein response (UPRmt): dead or alive?“
February 19th, 2018 Bernhard Lechtenberg,
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA
"The structure of the E2-ubiquitin/HOIP-RBR transfer complex: RBR E3 ligase mechanism and allosteric regulation by ubiquitin"
February 14th, 2018 Vivek Sharma,
Department of Physics and Institute of Biotechnology, University of Helsinki, Finland
"Adding dynamics to static structures - redox-coupled proton pumping in respiratory complex I"
January 31th, 2018 Dirk Daelemans,
Department of Microbiology and Immunology, Rega Institute, KU Leuven, Belgium
"Identifying the cellular target of bioactive molecules by CRISPR/Cas-mediated NHEJ mutagenesis scanning using tiling libraries"
September 20th, 2017 Jost Enninga,
Institute Pasteur, Department of Cell Biology and Infection Paris, France
"Visualizing the involvement of host pathways in Shigella and Salmonella induced membrane damage"
June 14th, 2017 Markus Bohnsack,
Institute for Molecular Biology, University medical center (UMG), Göttingen, Germany
"Turning RNA-protein complexes: the roles of RNA helicases and RNA modifications in health and disease"
June 08th, 2016 Thordur Oskarsson,
Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), German Cancer Research Center (DKFZ), Heidelberg, Germany
"Extracellular matrix proteins of stem cell niches: role in breast cancer metastasis"
Mini-symposium on Autophagy
October 28th, 2015 Patrice Codogno,
Institut Necker Enfants-Malades, INSERM U1151-CNRS UMR 8253, Paris, France.
"Autophagy and primary cilia in stress response"
October 28th, 2015 Nicholas Ktistakis,
Signalling Department, Babraham Institute, Cambridge, UK.
"Starvation-induced and selective autophagy: the first 3 minutes"
September 16th, 2015 Eric Fischer + Bennett,
Eric Fisher: Cancer Biology, Dana-Farber Cancer Institute & BCMP, Harvard Medical School
"Subversion of host cell function by Chlamydia"
Eric Bennet: Division of Biological Sciences, University of California-San Diego (UCSD)
"Ubiquitin-dependent control mechanisms that govern protein homeostasis"
September 14th, 2015 Hagai Abeliovich,
Robert H. Smith Faculty of Agriculture, Food and Environment Hebrew University of Jerusalem, Israel
"Mitochondrial autophagy: How do cells select what to degrade?"
February 26th, 2015 Daniel Abankwa,
Turku Centre for Biotechnology University of Turku and Abo Akademi University BioCity, Turku, Finland.
"Targeting the nanoscale signaling architecture of Ras in cancer and cancer stem cells"
February 11th, 2015 Naoko Mizuno,
Max Planck Institute of Biochemistry, Martinsried, Germany.
"Structural basis for the extended CAP-Gly domains of p150 binding to microtubules and its implication for tubulin dynamics"
December 12th, 2014 Manuel Kaulich,
Dept. Cellular & Molecular Medicine, UCSD - School of Medicine, La Jolla, USA.
"Determining G1 Restriction Point Control by Gene-Editing and Single-Cell Analysis" <
November 03th, 2014 James Olzman,
Seminar in Biochemistry.
University of California, Berkeley Nutritional Science & Technology Berkeley, CA, USA
"At the intersection of ER protein quality control and lipid droplets" <
December 11th, 2013 Simon Wilkinson,
To be announced.
November 27th, 2013 Fulvio Reggiori,
Department of Cell Biology, Cell Microscopy Centre and Institute of Biomembranes, University Medical Center Utrecht
"Coronaviruses hijack LC3-I positive EDEMosome membranes for replication."
July 03th, 2013 Thomas Wollert,
MPI of Biochemistry, Martinsried. Germany
"A coat that fits all sizes: Molecular mechanism of autophagosome biogenesis"
June 21th, 2013 Anindya Dutta,
Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA
"HRe-replication and microDNAs, two types of genomic instability in normal and cancer cells"
June 11th, 2013 Sharad Kumar,
Centre for Cancer Biology, SA Pathology, Adelaide, Australia
"Nedd4 family of ubiquitin ligases in physiology and disease"
June 05th, 2013 Franz Herzog,
Gene Center Ludwig-Maximilians-Universität München, Germany
"Identifying Missing Links in Structrual Biology and Interaction Proteomics"
May 22th, 2013 Varatharajan Sundaramurthy,
Max-Planck-Istitute of Cell Biology, Dresden, Germany
"An integrative approach to identify and exploit crucial host determinants of intracellular bacterial survival"
May 21th, 2013 Mike Matunis,
Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
"SUMOylation and Control of Progression through Mitosis"
February 25th, 2013 Attila Remenyi,
Department of Biochemistry, Eotvos Lorand University, Budapest, Hungary
"Protein-protein interactions that give sense to MAPK signalling"
November 21th, 2012 Jörg Höhfeld,
Institute for Cell Biology, University Bonn
"Cellular mechanotransduction relies on tension-induced und chaperone-assisted autophagy"
November 17th, 2012 Konstanze Winkelhofer,
October 08th, 2012 Yaron Galanty,
Gurdon Institut, University of Cambridge
September 25th, 2012 Caudio Joazeiro,
Department of Cell Biology The Scripps Research Institute La Jolla, CA, USA
"The E3 Ligase Listerin/Ltn1 is implicated in neurodegeneration and mediates a novel pathway of protein quality control."
September 18th, 2012 Brenda Schulman,
Howard Hughes Medical Institute, St. Jude Children's Research Hospital
"Twists and turns in ubiquitin conjugation cascades"
March 21th, 2011 Fraser Coxon,
Department for Medicine & Therapeutics, Institute of Medical Sciences, University of Aberdeen, UK
"Insights into osteoclast cell biology from studies of the bone disease osteopetrosis"
October 05th, 2011 Alexander Buchberger,
Theodor-Boveri-Institut, Universität Würzburg, Germany
"The AAA ATPase Cdc48/p97 and its cofactors"
February 01th, 2010 Henning Walczak,
Imperial College London, Hammersmith Hospital, London, UK<br />
"The importance of linear ubiquitination at the apex of the TNF
signal transduction cascade"
March 03th, 2010 Ernst Stelzer,
European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
"Light sheet based fluorescence microscopes (LSFM, SPIM, DSLM) reduce phototoxic effects by several orders of magnitude"
August 31th, 2010 Wade Harper,
IBC II and FMLS Lecutre
Department of Pathology, Harvard Medical School, Boston, MA, USA
"Proteomic and Genetic analysis of the Ubiquitin system"
This seminar takes place in building 22 lecture hall 2 at 17.00 h.
October 06th, 2010 Jonathan Howard,
Institute for Genetics, University Cologne, Cologne
"Cell biology of a novel resistance mechanism in the mouse against the protozoan parasite, oxoplasma gondii: something for Everybody"
October 28th, 2010 Gudula Schmidt,
Institute for Experimental and Clinical Pharmacology and Toxicology
University of Freiburg
"Molecular strategies of pathogenic bacteria – toxins control Rho GTPases"
January 28th, 2009 Benno Jungblut,
PhD, MPI für Herz und Lungenforschung
"Genetic Control of Cell Behavior during Zebrafish Heart Morphogenesis"
February 10th, 2009 Pascale COSSARD
, Institut Pasteur, Paris, France
“The Bacterial Pathogen Listeria monocytogenes: the Rise of a Mutifacted Model”
March 12th, 2009 Elizabeth BLACKBURN
University of California San Francisco, USA
March 20th, 2009 Susumu TONEGAWA
Massachusetts Institute of Technology, Cambridge, USA
“Neural Mechanisms for Memory”
March 24th, 2009 Wade Harper,
Frankfurt Ubiquitin meeting 2009 :
Regulation of the proteasome via uiquitin chain dynamics
Dan Finley, Integrating proteomic and RNAi studies identifies new modules in ubiquitin and checkpoint signaling
Both from Harvard University Boston, USA
April 01th, 2009 Soichi Wakatsuki,
Structural Biology Research Center Institute of Materials Structure Science Photon Factory, KEK, Japan
"Structural insights into ubiquitin recognition in vesicle transport and signal transduction: ESCRT pathway and Finding NEMO"
June 23th, 2009 Venki RAMAKRISHNAN
MRC Laboratory of Molecular Biology, Cambridge, UK
“Induced fit: A common strategy used by the Ribosome”
September 16th, 2009 Matthias Husmann
, Institut für Medizinische Mikrobiologie und Hygiene, Johannes Gutenberg Universität Mainz
"Influential circles: pore forming toxins challenge cellular self-defense"
September 21th, 2009 Kazuhiro Iwai
Department of Biophysics and Biochemistry, Graduate School of Medicine, Osaka University,
„Linear Polyubiquitination: A newly identified regulator Involved of NF-kB signalling"
November 17th, 2009 Philip COHEN
Scottish Institute for Cell Signalling College of Life Science, University of Dundee, UK
January 22th, 2008 Josef Penninger,
Institte of Molecular Biotechnology GmbH, Vienna, Austria
"From Systems Genetics in Flies to human Medicine"
March 14th, 2008 Tim Mosmann,
Center for Vaccine Biology and Immunology, University of Rochester Medical Center, USA "Title pendingl"
April 30th, 2008 Thomas Sommer,
Max-Delbrück-Center for Molecular Medicine, Berlin
"The HRD Ubiquitin Ligase and Protein Quality Control in the Secretory Pathway"
May 14th, 2008 >Manolis Pasparakis,
Institute for Genetics, University of Cologne
"IKK/NF-*B signaling in inflammation and cancer"
May 19th, 2008 Patrick Matthias, Friedrich Miescher,
Institute for Biochemical Research (FMI), Basel, Switzerland
"Analysis of Histone deacetylase function in the lymphoid system and beyond"
May 23th, 2008 Yosef Yarden Weizmann,
Institute of Science, Israel
"EGFR and HER2: an oncogenic alliance and targets for cancer therapies"
July 12th, 2008 Kanti Bhoola,
University Perth, Australia
"Epigenetics and Cancer"
August 12th, 2008 Oliver Anderka,
Sanofi-Aventis Deutschland, Frankfurt
"Biophysical characterization of protein-compound and protein-protein interactions"
August 12th, 2008 Tony Pawson,
Samuel Lunenfeld Research Institute, Mt Sinai Hospital, University of Toronto, Canada "SH2 domains and tyrosine kinases - back to the future"
November 05th, 2008 Tony Pawson,
Samuel Lunenfeld Research Institute, Mt Sinai Hospital, University of Toronto, Canada
"SH2 domains and tyrosine kinases - back to the future"
November 18th, 2008 Peter Walter,
University of California, San Francisco, USA
"Protein Homeostasis in Health and Disease"
November 25th, 2008 Edward A. Dennis,
University of California, San Diego, USA
"Eicosanoid Lipidomics and Phospholipase A2 Role in Inflammatory Disease"
December 05th, 2008 Dr. Vishva Dixit,
Physiological Chemistry, Genentech