Seminars in Biochemistry

2019

November 13th, 2019   Malavika Raman
Tufts University School of Medicine
Department of Developmental, Molecular and Chemical Biology
Boston, USA
"Tête-à-tête: The p97-UBXD8 complex regulates ER-mitochondrial contact sites"  

October 23th, 2019   Marcel Schulz
Max-Planck-Institut für Informatik
High-throughput Genomics & Systems Biology
Saarbrücken, Germany
"Understanding transcriptional regulation from large-scale epigenomics data"  

October 9th, 2019   Katharina Imkeller
German Cancer Research Center,
Heidelberg, Germany
"Mathematical modeling of pooled CRISPR screens to decrease experiment size and improve phenotype detection"  

July 10th, 2019   Konstanze Winklhofer
Institute for Biochemistry and Pathobiochemistry
Ruhr-University, Bochum
"A Role of Linear Ubiquitination in Protein Quality Control: Implications for Neurodegenerative Diseases"  

June 19th, 2019   Boris Pfander
Max-Planck Institute of Biochemistry
Martinsried, Germany
"Deciphering and manipulating the response to DNA breaks"  

June 12th, 2019   Irmgard Sinning
Biochemistry Centre of the University of Heidelberg
Heidelberg, Germany
"Ribosome associated chaperones in cotranslational protein folding"  

May 08th, 2019   Andreas Pichlmair
Institute of Virology
TU Munich, Germany
"Intracellular organization of the innate response – and its disturbance by viruses"  

March 12th, 2019   Dorothee Dormann
Biomedical Center (BMC)
LMU Munich, Germany
"Molecular mechanisms of neurodegeneration - from nuclear transport defects to aberrant phase seperation"  

March 06th, 2019   Markus Diefenbacher
Department of Biochemistry and Molecular Biology
University of Wuerzburg
"Targeting deregulated protein stability in lung and colorectal cancer"  

February 04th, 2019   Fumiyo Ikeda
Institute of Molecular Biotechnology
Vienna, Austria
"The IAP proteins in the regulation of autophagy"  

2018

 

December 14th, 2018 Marius Lemberg
Center for Molecular Biology, Heidelberg University Heidelberg, Germany
"Analysis of intramembrane proteolysis: from fluorescent timers to genomic tagging" 

December 10th, 2018 Markus Diefenbacher (CANCELED)
Department of Biochemistry and Molecular Biology University of Würzburg, Germany
"Targeting deregulated protein stability in lung and colorectal cancer" 

December 04th, 2018 Konstanze Winklhofer (Seminar in Biochemistry & SFB1177 seminar)
Institute for Biochemistry and Pathobiochemistry, Ruhr-University, Bochum, Germany
"A Role of Linear Ubiquitination in Protein Quality Control: Implications for Neurodegenerative Diseases" 

November 29th, 2018 Davide Cacchiarelli
Telethon Institute of Genetics and Medicine (TIGEM) Naples, Italy
"Aligning single-cell trajectories identifies molecular determinants of cell fate decisions" 

November 22th, 2018 Björn Papke
University of North Carolina at Chapel Hill, USA
"The KRAS oncogene: Know your enemy" 

November 07th, 2018 Peter Rehling
Institute of Cell Biochemistry, University Medical Center, Göttingen, Germany
"Mitochondrial biogenesis: Integrating mitochondrial functions into the cellular context" 

November 01th, 2018 Aditya Murthy
Genentech Inc., Department of Cancer Immunotherapy and Hematology, South San Francisco, CA, USA
"Leveraging mass spectrometry and genome editing to study innate immunity" 

October 31th, 2018 Dimitris Liakopoulos
Cell Biology Research Center, Montpellier, France
"Spindle organization through polyvalent protein interactions" 

September 21th, 2018 Luke Wiseman
Associate Professor, Dept. of Molecular Medicine, The Scripps Research Institute MEM220, La Jolla, California
"Unexpected Outcomes: Non-secretory functions of the Unfolded Protein Response" 

August 29th, 2018 Joachim Weis
Institute of Neuropathology University Hospital Aachen Aachen, Germany
"Neuropathology of the endoplasmic reticulum in neurodegenerative and neuromuscular diseases" 

July 13th, 2018 Renata Pasqualini and Wadih Arap
Rutgers Cancer Institute of New Jersey, Newark, New Jersey, USA
"Ligand-directied Targeting & Molecular Imaging in Translational Medicine" 

July 04th, 2018 Elke Deuerling
Department of Biology, University of Konstanz, Germany
"Protein folding in the cell: Chaperones acting at central hubs of proteostasis" 

June 22th, 2018 Marco Hein
Department of Cellular Molecular Pharmacology, University of California, San Francisco, USA
"Dissecting cytomegalovirus infection using CRISPRi/n and single-cell transcriptomics" 

June 08th, 2018 Craig Crews
Institute of Cancer Research, Medical University of Vienna, Austria
"PROTAC-mediated Protein Degradation: A New Therapeutic Modality" 

June 06th, 2018 Maria Sibilia
Institute of Cancer Research, Medical University of Vienna, Austria
"Cell-specific functions of EGFR in inflammation and cancer" 

May 09th, 2018 Broder Schmidt
Stanford University School of Medicine, Stanford, CA, USA
"‘Phasing in’ on the properties and functions of intracellular liquid phases"

April 23th, 2018 Don Kirkpatrick
Genentech, South San Francisco, CA, USA
"Proteomic tools for investigating inducible degradation" 

April 18th, 2018 Goran Stjepanovic
University of California, Berkeley, CA, USA
"Molecular mechanisms of autophagy initiation" 

March 16th, 2018 Aitor Hierro
CIC bioGUNE, Derio, Spain
"TBA" 

February 28th, 2018 Alexandra Trifunovic
CECAD Research Center, University of Cologne, Germany
"Mammalian mitochondrial unfolded protein response (UPRmt): dead or alive?“ 

February 19th, 2018 Bernhard Lechtenberg,
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA
"The structure of the E2-ubiquitin/HOIP-RBR transfer complex: RBR E3 ligase mechanism and allosteric regulation by ubiquitin" 

February 14th, 2018 Vivek Sharma,
Department of Physics and Institute of Biotechnology, University of Helsinki, Finland
"Adding dynamics to static structures - redox-coupled proton pumping in respiratory complex I" 

January 31th, 2018 Dirk Daelemans,
Department of Microbiology and Immunology, Rega Institute, KU Leuven, Belgium
"Identifying the cellular target of bioactive molecules by CRISPR/Cas-mediated NHEJ mutagenesis scanning using tiling libraries"

 

 

2017

 

November 22th, 2017 Agnieszka Chacińska,
International Institute of Molecular and Cell Biology Warsaw, Poland
"Crosstalk of mitochondria and cellular protein homeostasis"

October 18th, 2017 Zoya Ignatova,
University of Hamburg, Hamburg, Germany
"Silent mutations speak out: tRNAs in adaptive translation and diseases"

 

September 20th, 2017 Jost Enninga,
Institute Pasteur, Department of Cell Biology and Infection Paris, France
"Visualizing the involvement of host pathways in Shigella and Salmonella induced membrane damage"

 

September 18th, 2017 Eyal Gottlieb,
Technion-Israel Institue of Technology, Haifa, Israel
"The onco-metabolic role and liabilities of the TCA cycle in cancer"

 

September 04th, 2017 Jochen Weishaupt,
Neurology Department, Ulm University, Ulm, Germany
"Genetics of ALS"

 

August 15th, 2017 Anne Schreiber,
ETH Zürich Institute of Biochemistry Zürich, Switzerland
"Regulation of Autophagy by the Atg1 kinase"

 

June 28th, 2017 Johannes Herrmann, 
Technical University Kaiserslautern Kaiserslautern, Germany
"Biogenesis of mitochondrial proteins"

 

June 22th, 2017 Kosuke Yusa,
Wellcome Trust Sanger Institute, Cambridge, UK
"Development and application of CRISPR-based loss-of-function screening"

 

June 14th, 2017 Markus Bohnsack,
Institute for Molecular Biology, University medical center (UMG), Göttingen, Germany
"Turning RNA-protein complexes: the roles of RNA helicases and RNA modifications in health and disease"

 

May 23th, 2017 Christian Ungermann,
University of Osnabrück, Germany
"Insights into the recruitment and activation of the Rab7-like Ypt7 protein during endosomal maturation"

 

May 03th, 2017 Martin Ott,
Stockholm University, Stockholm, Sweden
"Mitochondrial translation efficiency modulates cellular proteostasis and stress signaling"

 

April 03th, 2017 John Rohde,
Department of Microbiology and Immunology, Dalhousie University Halifax, Canada
"Shigella as a tool to explore the ubiquitinbacterial pathogen interface"

 

February 08th, 2017 Markus Elsner,
Senior Editor, Nature Biotechnology
"Publishing in Nature journals"

 

2016

 

September 28th, 2016 Robert Ernst,
BMLS - Goethe University Frankfurt, Germany
"A new hope in functional genomics: genetic screens with CRISPR technology"

 

September 28th, 2016 Robert Ernst,
BMLS - Goethe University Frankfurt, Germany
"Eukaryotic sensors for membrane compositions - importance of intra-membrane sensing"

 

September 14th, 2016 Holger Richly,
Institute of Molecular Biology gGmbH (IMB), Mainz, Germany
"Late-life inhibition of key autophagy genes extends C.elegans lifespan"

 

June 08th, 2016 Thordur Oskarsson,
Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), German Cancer Research Center (DKFZ), Heidelberg, Germany
"Extracellular matrix proteins of stem cell niches: role in breast cancer metastasis"

 

May 25th, 2016 Nirmal Robinson,
CECAD Research Center, University of Cologne, Cologne, Germany
"Metabolic Regulation of Cell Autonomous Immune defense against S. Typhimurium"

 

May 18th, 2016 Andrea Pichler,
Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
"Sumo Rules"

 

May 13th, 2016 Brian Caudill,
Integrated DNA Technologies, BVBA, Leuven, Belgium
"Building new tools for more potent CRISPR-Cas9 Genome Editing"

 

April 27th, 2016 Boris Pfander,
Max-Planck Institute of Biochemistry, Martinsried, Germany
"How to prevent and deal with replication stress"

 

March 09th, 2016 Carmine Settembre,
Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy
"Roles and regulators of autophagy during skeletal growth"

 

March 02th, 2016 Wilfried Roth,
Institute for Pathology Johannes Gutenberg-Universität Mainz Germany
"Pathology of cell death"
(Taking place at the Georg-Speyer-Haus)

 

February 09th, 2016 Shravan Kumar Mishra,
Indian Institute of Science Education and Research (IISER) Mohali, India
"Ubiquitin- like processing generates an intron-specific RNA splicing factor"

 

2015

 

Mini-symposium on Autophagy

October 28th, 2015 Patrice Codogno,
Institut Necker Enfants-Malades, INSERM U1151-CNRS UMR 8253, Paris, France.
"Autophagy and primary cilia in stress response"

October 28th, 2015 Nicholas Ktistakis,
Signalling Department, Babraham Institute, Cambridge, UK.
"Starvation-induced and selective autophagy: the first 3 minutes"

 

 

October 15th, 2015 Lilliana Radoshevich,
Institut Pasteur Paris, France
"ISG15 counteracts Listeria monocytogenes infection"

 

September 28th, 2015 Hind Medyouf,
Georg-Speyer-Haus Institute for Tumor Biology, Frankfurt, Germany
"Clonal Heterogeneity and Niche Dependency in Human Myelodysplasia"

 

September 16th, 2015 Eric Fischer + Bennett,
Eric Fisher: Cancer Biology, Dana-Farber Cancer Institute & BCMP, Harvard Medical School
"Subversion of host cell function by Chlamydia"

Eric Bennet: Division of Biological Sciences, University of California-San Diego (UCSD)
"Ubiquitin-dependent control mechanisms that govern protein homeostasis"

 

September 14th, 2015 Hagai Abeliovich,
Robert H. Smith Faculty of Agriculture, Food and Environment Hebrew University of Jerusalem, Israel
"Mitochondrial autophagy: How do cells select what to degrade?"

 

July 20th, 2015 Thomas Rudel,
Chinese Academy of Sciences, Institute of Biochemistry and Cell Biology, Shanghai, China.
"A Kinase Initiated Death Pathway"

 

May 27th, 2015 Liming Sun,
Biozentrum der Universität Würzburg, Department of Microbiology, Würzburg, Germany
"Subversion of host cell function by Chlamydia"

 

May 20th, 2015 Huib Ovaa,
NKI Amsterdam, Netherlands.
"Development and use of ubiquitin-based reagents"

 

May 13th, 2015 Hannelore Ehrenreich,
Clinical Neuroscience Max Planck Institute for Experimental Medicine Göttingen, Germany.
"Autism: A disease of the synapse – search for mechanistic insight"

 

April 29th, 2015 Sascha Martens,
Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.
"Molecular Mechanisms of Selective Autophagy"

 

March 25th, 2015 Anton Wellstein,
Georgetown University Medical School, Lombardi Comprehensive Cancer Center, Washington DC, USA.
"The Hippo pathway in cancer malignant progression"

 

March 24th, 2015 Tilmann Bürckstümmer,
Horizon Genomics GmbH Campus Vienna Biocenter Vienna, Austria.
"An efficient pipeline for CRISPR/Cas-mediated genome engineering in haploid human cells"

 

February 26th, 2015 Daniel Abankwa,
Turku Centre for Biotechnology University of Turku and Abo Akademi University BioCity, Turku, Finland.
"Targeting the nanoscale signaling architecture of Ras in cancer and cancer stem cells"

 

February 11th, 2015 Naoko Mizuno,
Max Planck Institute of Biochemistry, Martinsried, Germany.
"Structural basis for the extended CAP-Gly domains of p150 binding to microtubules and its implication for tubulin dynamics"

 

January 28th, 2015 Alexander Höllein,
Technische Universität München, Germany
"Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma - mechanistic insights"

 

January 21th, 2015 Henning Urlaub,
Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
"The potential of mass-spectrometric proteomics for cell biological and biomedical research"

 

2014

 

December 12th, 2014 Manuel Kaulich,
Dept. Cellular & Molecular Medicine, UCSD - School of Medicine, La Jolla, USA.
"Determining G1 Restriction Point Control by Gene-Editing and Single-Cell Analysis" <

 

November 03th, 2014 James Olzman,
Seminar in Biochemistry.
University of California, Berkeley Nutritional Science & Technology Berkeley, CA, USA
"At the intersection of ER protein quality control and lipid droplets" <

 

October 08th, 2014 Maja Köhn,
EMBL Heidelberg, Genome Biology Unit Heidelberg, Germany.
"Chemical activation of protein phosphatase-1 as a tool to study its roles in health and disease" <

 

June 25th, 2014 Michael Hensel,
Department for Microbiology university Osnabrück.
"The intracellular lifestyle of Salmonella enterica: a new view on manipulations of the endosomal system" <

 

June 13th, 2014 Martin Scheffner,
Seminar in Biochemistry.
"The ubiquitin ligase E6AP and its role in human disease" <

 

June 04th, 2014 Carsten Sachse,
Seminar in Biochemistry.
"Cryo-EM studies of autophagy receptor p62 – towards a mechanism of selective autophagy"" <

 

May 07th, 2014 Hemmo Meyer,
Seminar in Biochemistry.
"The ubiquitin-dependent segregase VCP/p97 governs endosomal sorting and autophagy" <

 

April 23th, 2014 Rajesh Gokhale,
Seminar in Biochemistry.
"Enantiostasis Rewiring of Cellular Networks in Depigmenting Disorder Vitiligo" <

 

February 26th, 2014 Christian Ungermann,
University of Osnabrück.
"Novel functions of the yeast Rab7 GTPase in lysosome/vacuole biogenesis" <

 

February 19th, 2014 Sebastian Wagner,
Medizinische Klinik II, Goethe University Frankfurt.
"Decoding Ubiquitin signals by quantitative mass spectrometry" <

 

January 20th, 2014 Zvulun Elazar,
Department of Biological Chemistry The Weizmann Institute of Science Rehovot, Israel.
"Atg8 family members and early stages of autophagosome formation" <

 

2013

 

December 11th, 2013 Simon Wilkinson,
To be announced.

 

November 27th, 2013 Fulvio Reggiori,
Department of Cell Biology, Cell Microscopy Centre and Institute of Biomembranes, University Medical Center Utrecht
"Coronaviruses hijack LC3-I positive EDEMosome membranes for replication."

 

November 22th, 2013 Thomas Sommer,
Max-Delbrück-Center for Molecular Medicine and Humboldt-University zu Berlin.
"Protein Export from the Endoplasmic Reticulum involves a channel formed by Der1"

 

November 07th, 2013 David Toczyski,
Department of Biochemistry and Biophysics University of California, San Francisco USA.
"to be announced"

 

September 18th, 2013 Karin Kühnel,
Department of Neurobiology MPI for Biophysical Chemistry Göttingen, Germany.
"Structural and functional characterization of PROPPINs"

 

July 03th, 2013 Thomas Wollert,
MPI of Biochemistry, Martinsried. Germany
"A coat that fits all sizes: Molecular mechanism of autophagosome biogenesis"

 

June 21th, 2013 Anindya Dutta,
Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA
"HRe-replication and microDNAs, two types of genomic instability in normal and cancer cells"

 

June 11th, 2013 Sharad Kumar,
Centre for Cancer Biology, SA Pathology, Adelaide, Australia
"Nedd4 family of ubiquitin ligases in physiology and disease"

 

June 05th, 2013 Franz Herzog,
Gene Center Ludwig-Maximilians-Universität München, Germany
"Identifying Missing Links in Structrual Biology and Interaction Proteomics"

 

May 22th, 2013 Varatharajan Sundaramurthy,
Max-Planck-Istitute of Cell Biology, Dresden, Germany
"An integrative approach to identify and exploit crucial host determinants of intracellular bacterial survival"

 

May 21th, 2013 Mike Matunis,
Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
"SUMOylation and Control of Progression through Mitosis"

 

February 25th, 2013 Attila Remenyi,
Department of Biochemistry, Eotvos Lorand University, Budapest, Hungary
"Protein-protein interactions that give sense to MAPK signalling"

 

2012

 

February 20th, 2012 Shravan Kumar Mishra,
Department of Molecular Cell Biology Max Planck Institute of Biochemistry Martinsried
"Ubiquitin-like modifiers and regulation of RNA splicing"

 

March 09th, 2012 Christian Kubisch,
Institute of Human Genetics University of Ulm
"Human Genetics as a means to identify novel disease-associated genes and to elucidate gene function"

 

November 21th, 2012 Jörg Höhfeld,
Institute for Cell Biology, University Bonn
"Cellular mechanotransduction relies on tension-induced und chaperone-assisted autophagy"

 

November 17th, 2012 Konstanze Winkelhofer,
Ludwig-Maximilians-University Munich

 

October 08th, 2012 Yaron Galanty,
Gurdon Institut, University of Cambridge

 

September 25th, 2012 Caudio Joazeiro,
Department of Cell Biology The Scripps Research Institute La Jolla, CA, USA
"The E3 Ligase Listerin/Ltn1 is implicated in neurodegeneration and mediates a novel pathway of protein quality control."

 

September 18th, 2012 Brenda Schulman,
Howard Hughes Medical Institute, St. Jude Children's Research Hospital
"Twists and turns in ubiquitin conjugation cascades"

 

2011

 

March 10th, 2011 Sarit Larisch,
Biology Department, University of Haifa, Mount Carmel, Haifa, Israel
"The ARTS connection; Apoptosis, Mitochondria and Tumor suppression"

 

March 15th, 2011 John Silke,
Department of Biochemistry, La Trobe University, Victoria, Australia
"The regulation of TNF signalling and Immunity by IAPs"

 

March 21th, 2011 Fraser Coxon,
Department for Medicine & Therapeutics, Institute of Medical Sciences, University of Aberdeen, UK
"Insights into osteoclast cell biology from studies of the bone disease osteopetrosis"

 

March 25th, 2011 Margaret Frame,
Edinburgh Cancer Research Centre, Edinburgh, UK
"Adhesion signalling in cancer processes"

 

October 05th, 2011 Alexander Buchberger,
Theodor-Boveri-Institut, Universität Würzburg, Germany
"The AAA ATPase Cdc48/p97 and its cofactors"

 

2010 & Before

 

January 20th, 2010 Matthias Peter,
ETH Zürich, Swizerland

 

January 22th, 2010 Arne Östman,
Cancer Center Karolinska, Karolinska Institutet, Sweden
"Cancer-associated fibroblasts; a source of novel candidate biomarkers and drug targets"

 

February 01th, 2010 Henning Walczak,
Imperial College London, Hammersmith Hospital, London, UK<br />
&quot;The importance of linear ubiquitination at the apex of the TNF
signal transduction cascade&quot;

 

March 03th, 2010 Ernst Stelzer,
European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
"Light sheet based fluorescence microscopes (LSFM, SPIM, DSLM) reduce phototoxic effects by several orders of magnitude"

 

March 24th, 2010 Marcus Krüger,
Max-Planck-Institute for Heart and Lung Research Department of cardiac Development and Remodeling, Bad Nauheim, Germany

 

June 02th, 2010 Dirk Bumann,
Biozentrum, University Basel, Switzerland
"System-level analysis of Salmonella / host interactions during infection"

 

June 16th, 2010 Hermann Steller,
Howard Hughes Medical Institute, The Rockefeller University, New York, USA
"Death by Degradation: Regulation of apoptosis by the ubiquitin-proteasome system“

 

August 31th, 2010 Wade Harper,
IBC II and FMLS Lecutre
Department of Pathology, Harvard Medical School, Boston, MA, USA
"Proteomic and Genetic analysis of the Ubiquitin system"
This seminar takes place in building 22 lecture hall 2 at 17.00 h.

 

September 27th, 2010 Zvulun Elazar,
Department of Biological Chemistry The Weizmann Institute of Science, Rehovot, Israel
"Mechanism of autophagosomes biogenesis"

 

October 06th, 2010 Jonathan Howard,
Institute for Genetics, University Cologne, Cologne
"Cell biology of a novel resistance mechanism in the mouse against the protozoan parasite, oxoplasma gondii: something for Everybody"

 

October 22th, 2010 Michael Rape,
Department of Molecular and Cell Biology, University of California at Berkeley, USA
"Function and assembly of K11-linked ubiquitin chains "

 

October 28th, 2010 Gudula Schmidt,
Institute for Experimental and Clinical Pharmacology and Toxicology
University of Freiburg
"Molecular strategies of pathogenic bacteria – toxins control Rho GTPases"

 

January 28th, 2009  Benno Jungblut,
PhD, MPI für Herz und Lungenforschung
"Genetic Control of Cell Behavior during Zebrafish Heart Morphogenesis"

 

February 10th, 2009 Pascale COSSARD
, Institut Pasteur, Paris, France
“The Bacterial Pathogen Listeria monocytogenes: the Rise of a Mutifacted Model”

 

March 12th, 2009 Elizabeth BLACKBURN
University of California San Francisco, USA
Title pending,

 

March 20th, 2009 Susumu TONEGAWA
Massachusetts Institute of Technology, Cambridge, USA
“Neural Mechanisms for Memory”

 

March 24th, 2009 Wade Harper,
Frankfurt Ubiquitin meeting 2009 :
Regulation of the proteasome via uiquitin chain dynamics
Dan Finley, Integrating proteomic and RNAi studies identifies new modules in ubiquitin and checkpoint signaling
Both from Harvard University Boston, USA

 

April 01th, 2009 Soichi Wakatsuki,
Structural Biology Research Center Institute of Materials Structure Science Photon Factory, KEK, Japan
"Structural insights into ubiquitin recognition in vesicle transport and signal transduction: ESCRT pathway and Finding NEMO"

 

April 29th, 2009 Nathan Brady
German Cancer Research Center (DKFZ) Heidelberg, Germany
"Resolving the connections between apoptosis and autophagy: molecular cell biology meets systems biology"

 

May 20th, 2009 Boris Macek
Proteome Center Interfaculty Institute for Cell Biology University of Tübingen, Germany
"Quantitative proteomics in the analysis of biological signal transduction"

 

June 03th, 2009 Felix Randow
MRC Laboratory of Molecular Biology, Cambridge UK
"IKK family kinases in innate immunity: their regulation by adaptor proteins and ubiquitin"

 

June 10th, 2009 Wim van Hul
Medical and Veterinary Sciences University Antwerpen, Belgium
"The molecular genetics of too much bone"

 

June 17th, 2009 Alain Israël
Cell signaling and activation Institut Pasteur, France
"Regulation of the NF-kB signaling cascade"

 

June 23th, 2009 Venki RAMAKRISHNAN
MRC Laboratory of Molecular Biology, Cambridge, UK
“Induced fit: A common strategy used by the Ribosome”

 

July 06th, 2009 Benjamin G. Neel
Ontario Cancer Institute, Toronto, Canada
"The Ras/Map kinase syndromes"

 

July 08th, 2009 Ariel Stanhill
Department of Biochemistry Technion, Faculty of Medicine Haifa, Israel
"Mechanisms of proteasome adaptation to protein misfolding"

 

September 16th, 2009 Matthias Husmann
, Institut für Medizinische Mikrobiologie und Hygiene, Johannes Gutenberg Universität Mainz
"Influential circles: pore forming toxins challenge cellular self-defense"

 

September 21th, 2009 Kazuhiro Iwai
Department of Biophysics and Biochemistry, Graduate School of Medicine, Osaka University,
„Linear Polyubiquitination: A newly identified regulator Involved of NF-kB signalling"

 

November 17th, 2009 Philip COHEN
Scottish Institute for Cell Signalling College of Life Science, University of Dundee, UK

 

December 04th, 2009 Nancy Hynes
Friedrich Miescher Institute for Biomedical Research (FMI) Basel, Switzerland
"Targeting molecular alterations in breast cancer"

 

December 09th, 2009 Richard Marais
CR UK Centre for Cell and Molecular Biology The Institute of Cancer Research, London, UK
"RAF and RAS signalling in melanoma: biology and therapeutics"

 

December 16th, 2009 Joern Dengjel
FRIAS-LIFENET, Universität Freiburg, Germany
"Spatio-temporal protein dynamics during autophagy"

 

December 18th, 2009 Christian Behrends,
Department of Pathology, Harvard Medical School, Boston, USA
"Network organization of the human autophagy system"

 

January 22th, 2008 Josef Penninger,
Institte of Molecular Biotechnology GmbH, Vienna, Austria
 "From Systems Genetics in Flies to human Medicine"

 

March 14th, 2008 Tim Mosmann,
Center for Vaccine Biology and Immunology, University of Rochester Medical Center, USA "Title pendingl"

 

April 30th, 2008 Thomas Sommer,
Max-Delbrück-Center for Molecular Medicine, Berlin
"The HRD Ubiquitin Ligase and Protein Quality Control in the Secretory Pathway"

 

May 14th, 2008 >Manolis Pasparakis,
Institute for Genetics, University of Cologne
"IKK/NF-*B signaling in inflammation and cancer"

 

May 19th, 2008 Patrick Matthias, Friedrich Miescher,
Institute for Biochemical Research (FMI), Basel, Switzerland
"Analysis of Histone deacetylase function in the lymphoid system and beyond"

 

May 23th, 2008 Yosef Yarden Weizmann,
Institute of Science, Israel
"EGFR and HER2: an oncogenic alliance and targets for cancer therapies"

 

July 12th, 2008 Kanti Bhoola,
University Perth, Australia
"Epigenetics and Cancer"

 

August 12th, 2008 Oliver Anderka,
Sanofi-Aventis Deutschland, Frankfurt
"Biophysical characterization of protein-compound and protein-protein interactions"

 

August 12th, 2008 Tony Pawson,
Samuel Lunenfeld Research Institute, Mt Sinai Hospital, University of Toronto, Canada  "SH2 domains and tyrosine kinases - back to the future"

 

November 05th, 2008 Tony Pawson,
Samuel Lunenfeld Research Institute, Mt Sinai Hospital, University of Toronto, Canada
 "SH2 domains and tyrosine kinases - back to the future"

 

November 18th, 2008 Peter Walter,
University of California, San Francisco, USA
 "Protein Homeostasis in Health and Disease"

 

November 25th, 2008 Edward A. Dennis,
University of California, San Diego, USA
 "Eicosanoid Lipidomics and Phospholipase A2 Role in Inflammatory Disease"

 

December 05th, 2008 Dr. Vishva Dixit,
Physiological Chemistry, Genentech
"Ubiquitin editing"