Perspective Lectures in Molecular Medicine

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lectures (2018 - 2019)

• February 21th, 2018 - Andrea Ballabio

  Andrea Ballabio Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy Location: UKF, Building 20, Hall 5, Audimax Time: 18:15h »The Awesome Lysosome« Download CV Download Abstract

• April 09th, 2018 - Erika Holzbaur

  Erika Holzbaur Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA Location: UKF, Building 20, Hall 5, Audimax Time: 18:15h »Autophagy dynamics in neuronal homeostasis and neurodegeneration« Download CV Download Abstract

• October 25th, 2018 - Man-Wah Tan

  Man-Wah Tan Genentech Inc, Department of Infectious Diseases, South San Francisco, CA, USA Location: UKF, Building 20, Hall 5, Audimax Time: 18:15h »Inspired by Nature: Engineering Natural Products and Antibodies to Treat Bacterial Infections« Link to lab webpage Download Abstract

• December 03th, 2018 - Tony Hyman

  Tony Hyman Max-Planck-Institut für molekulare Zellbiologie und Genetik, Dresden Location: UKF, Building 22, Hall 22-1, Paul-Ehrlich-Audience Time: 16:00h »Biomolecular condensates and their implications for physiology and disease« Link to lab webpage Download Abstract

• December 12th, 2018 - Roland Lill

  Roland Lill Institut für Zytobiologie, Philipps-Universität Marburg Location: UKF, Building 20, Hall 5, Audimax Time: 18:15h »Biogenesis of iron-sulfur proteins in eukaryotes: A complex pathway for many different cellular functions« Link to lab webpage Download Abstract

• February 13th, 2019 - Vivek Malhotra

  Vivek Malhotra Centre for Genomic Regulation (CGR) Barcelona Biomedical Research Park, Barcelona, Spain Location: UKF, Building 20, Hall 5, Audimax Time: 18:15h »Building a Machine for Secretion of Bulky Collagens from Endoplasmic Reticulum« Link to webpage Download Abstract

• May 16th, 2019 - Wade Harper and Brenda Schulman

  Wade Harper and Brenda Schulman Harvard Medical School, Boston, MA, USA and Max Planck Institute of Biochemistry, Martinsried, Germany Location: UKF, Building 20, Hall 5, Audimax Time: 17:15h »Role of selective autophagy in cellular homeostasis and neurodegenerative disease« »Ubiquitin and mitosis: regulation by a molecular machine« Wade Harper: Link to webpage Download Abstract Brenda Schulman: Link to webpage Download Abstract

• July 02nd, 2019 - Reinhard Jahn

  Reinhard Jahn Max Planck Institute for Biophysical Chemistry, Goettingen, Germany Location: UKF, Building 20, Hall 5, Audimax Time: 18:15h »Membrane traffic in endosomes – how is targeting specificity achieved?« Link to webpage Download Abstract

• October 21th, 2019 - Jacob Corn

  Jacob Corn ETH Zürich, Zurich, Switzerland Location: UKF, Building 20, Hall 5, Audimax Time: 18:15h »CRISPR-Cas genome editing at work in human cells« Link to webpage Download Abstract

• (cancelled) March 26th, 2020 - Martin Beck

  Martin Beck Max-Planck-Institut für Biophysik, Frankfurt, Germany Location: UKF, Building 22, Hall 1, Paul-Ehrlich Lecture Hall Time: 18:15h »Solving a 3D jigsaw with 1000 pieces – Structure, assembly and turnoverof the nuclear pore complex« Link to webpage Download Abstract Download Poster

Previous lectures (2002 - 2017)

• April 25th, 2017 - Tamotsu Yoshimori

  Tamotsu Yoshimori Department of Genetics, Osaka University, Osaka, Japan »INSIGHTS INTO MEMBRANE DYNAMICS OF AUTOPHAGY AND ITS IMPLICATIONS IN DISEASES « Download CV Download Abstract Download Autobiography Download Publications

• October 26th, 2017 - Rene Bernards

  Rene Bernards The Netherlands Cancer Institute, Amsterdam, The Netherlands Location: University Hospital Frankfurt, Lecture Hall 22, Hall 1 » Finding new vulnerabilities of cancer cells for therapeutic benefit « Download CV Download Abstract

• November 17th, 2017 - Trey Ideker

  Trey Ideker University of California San Diego (UCSD), School of Medicine, La Jolla, USA Location: Building 20 - 5 (Audimax) » Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy « Download CV Download Abstract

• December 01th, 2017 - Claudio Joazeiro

  Claudio Joazeiro ZMBH, University Heidelberg, Heidelberg, Germany Location: UKF, Building 23, Hall 3 » Ribosome-Associated Protein Quality Control (RQC) and Neurodegeneration « Download CV Download Abstract

• May 03th, 2016 - Dirk Bumann

  Dirk Bumann Biozentrum Basel, University of Basel, Switzerland »Pathogen heterogeneity during infection: impact on disease progression and therapy« Download CV Download Abstract

• June 01th, 2016 - Joan Massagué

  Joan Massagué Memorial Sloan Kettering Cancer Center, NY, USA »Metastatic Colonization by Circulating Tumor Cells« Download CV Download Abstract

• October 12th, 2016 - Ralph Nixon

  Ralph Nixon Department of Psychiatry, NYU School of Medicine, NY, USA »The pathogenic role of defective endosomal-lysosomal function in Alzheimer's disease« Georg-Speyer-Haus, Lecture hall ground floor Paul-Ehrlich-Straße 42-44, Frankfurt Download CV Download Abstract

• December 07th, 2016 - Dario Alessi

  Dario Alessi MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dundee, UK. »Disruptions on the highways of cellular signalling« Klinikum der Johann Wolfgang Goethe-Universität, Hörsaalgebäude 22-1, Theodor-Stern-Kai 7, Frankfurt Download CV Download Publications Download Abstract

• March 13th, 2015 - James P. Allison

  James P. Allison The University of Texas MD Anderson Cancer Center, Houston, TX, USA »Immune Checkpoint Blockade in Cancer Therapy: New Insights, opportunities and prospects for a Cure« Download CV Download Publications

• May 05th, 2015 - Wolfgang Baumeister

  Wolfgang Baumeister Max-Planck-Institute of Biochemistry, Martinsried, Germany »Electron Cryomicroscopy and Cellular Pathology« Download CV

• June 08th, 2015 - David Vaux

  David Vaux Institute of Medical Research, Walter and Eliza Hall, Melbourne, Australia »Targeting IAP and Bcl-2 family proteins to treat cancer« Download CV Download Publications Download Abstract

• July 03th, 2015 - Tadatsugu Taniguchi

  Tadatsugu Taniguchi Department of Molecular Immunology, Institute of Industrial Science, The University of Tokyo, Tokyo, Japan »Recognition of self-derived molecules in the regulation of inflammation and anti-tumor immunity« Download CV Download Publications

• March 12th, 2014 - Michael Reth

  Sharon Tooze Cancer Research UK London Research Institute, London, GB »Regulation of autophagosome formation in mammalian cells« Download CV Download Abstract Download Publications

• March 12th, 2014 - Michael Reth

  Michael Reth Max Planck Institute of Immunobiology and Epigenetics, University of Freiburg, German »Sensing the unknown for antibody production: From the side chain theory to the dissociation activation model« Download CV Download Publications Download Abstract

• April 29th, 2014 - Volker Haucke

  Volker Haucke Leibniz-Institut für Molekulare Pharmakologie, Berlin, Germany »Spatiotemporal control of endocytosis - from mechanisms to synaptic function« Download CV Download Abstract

• May 13th, 2014 - K. C. Nicolaou

  K. C. Nicolaou The Scripps Research Institute, La Jolla, CA, USA »Total Synthesis of Rare Natural and Designed Molecules of Biological and Medical Importance« Download CV Download Publications Download Abstract

• November 18th, 2014 - Elena Conti

  Elena Conti Max Planck Institute of Biochemistry, Martinsried, Germany »the exosome complex in RNA processing and decay« Download CV Download Publications Download Abstract

• October 22th, 2013 - Susan Lindquist

  Susan Lindquist Whitehead Institute for Biomedical Research, Nine Cambridge Center, Massachusetts, USA »A rapid discovery platform for protein folding diseases« Download CV Download Publications Download Publications

• September 02th, 2013 - Randy Schekman

  Randy Schekman Li Ka Shing Center, UC Berkeley, CA, USA »Cargo sorting into transport vesicles: Mechanism and relation to mammalian development« Download CV Download Publications Download Abstract

• May 08th, 2013 - Helmut Grubmüller

  Helmut Grubmüller Max Planck Institute for Biophysical Chemistry Göttingen, Germany »Mechanoenzymatics: Conformational Dynamics of Biomolecules« Download CV Download Publications Download Abstract

• April 16th, 2013 - Eric Olson

  Eric Olson University of Texas Dallas, USA »The Molecular Circuitry of Heart Development, Disease and Regeneration« Download CV Download Publications Download Abstract

• March 05th, 2013 - Rüdiger Klein

  Rüdiger Klein Max Planck Institute of Neurobiology Martinsried, Germany »Molecular principles of axon guidance« Download CV Download Abstract

• May 22th, 2012 - Ronald BreakerRonald Breaker

  Ronald Breaker Department of Molecular, Cellular and Developmental Biology, Yale University, USA »Antibiotics and Riboswitches« Download CV

• March 13th, 2012 - Peter Walter

  Peter Walter Department of Biochemistry & Biophysics, University of California, San Francisco »The Unfolded Protein Response in Health and Disease« Download CV Download Publications

• February 07th, 2012 - Reinhard Jahn

  Reinhard Jahn Max-Planck-Institut für biophysikalische Chemie Göttingen, Deutschland »Signalling between neurons – how nerve cells speak to each other«

• November 08th, 2011 - Axel Ullrich

  Axel Ullrich Max Planck Institute for Biochemistry, Dept. of Molecular Biology, Martinsried, Germany »30 Years of Molecular Medicine: Oncogenomics towards Novel Cancer Therapies«

• September 20th, 2011 - Raymond J. Deshaies

  Raymond J. Deshaies Ph.D.Professor, CaltechInvestigator, Howard Hughes Medical Institute, California USA »Mechanisms, and regulation of cullin-RING ubiquitin ligases«

• May 24th, 2011 - Ronald M. Evans

  Ronald M. Evans Howard Hughes Medical Institute La Jolla, CA, USA »Nuclear Receptors and AMPK – Resetting Metabolism«

• January 25th, 2011 - Jennifer Lippincott-Schwartz

  Jennifer Lippincott-Schwartz Section on Organelle Biology, NICHD, NIH, Bethesda, MD, USA »Seeing Cells in Action with Photoactivatable Fluorescent Proteins« Download CV

• November 16th, 2010 - Dr. F. Ulrich Hartl

  Dr. F. Ulrich Hartl Director Department of Cellular Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany »Chaperone-assisted protein folding in health and disease« Download CV

• September 21th, 2010 - Tim HUNT

  Tim Hunt Cancer Research UK, Herts, UK »New Elements in the Control of Mitosis: Fresh Light on Protein Phosphatases« Download CV <

• July 06th, 2010 - Edmond H. Fischer

  Edmond H. Fischer Department of Biochemistry, University of Washington, Seattle, WA, USA »The Origin of Reversible Phosphorylation« Download CV Download Publications

• May 19th, 2010 - C. Ronald Kahn

  C. Ronald Kahn Joselin Diabetes Center and Harvard Medical School, Boston, USA »Critical Nodes in Insulin Action and Insulin Resistance« Download CV

• February 10th, 2010 - Inder M. Verma

  Inder M. Verma Salk Institute for Bioalogical Studies La Jolla, USA »Cancer: A Malady of Genes« Download CV

• November 17th, 2009 - Philip Cohen

  Philip Cohen Scottish Institute for Cell Signalling College of Life Science, University of Dundee, UK »The Interplay between Protein Phosphorylation and Protein Ubiquitylation in Regulating the Innate Immune System« Download CV

• June 23th, 2009 - Venki Ramakrishnan

  Venki Ramakrishnan MRC Laboratory of Molecular Biology, Cambridge, UK »Induced fit: A common strategy used by the Ribosome«

• March 20th, 2009 - Susumu Tonegawa

  Susumu Tonegawa Massachusetts Institute of Technology Nobel Prize Medicine/Physiology 1987 »Neural Mechanisms for Memory« Download CV

• March 12th, 2009 - Elizabeth Blackburn

  Elizabeth Blackburn Department of Biochemistry and Biophysics University of California, San Francisco, USA Paul Ehrlich- und Ludwig Darmstädter Preisträgerin 2009 »Responses of Cells and Organisms to Perturbing Telomere Maintenance«

• February 10th, 2009 - Pascale Cossart

  Pascale Cossart Dept. Cell Biology and Infection, Institut Pasteur, Paris, France »The Bacterial Pathogen Listeria monocytogenes: the Rise of a Multifaceted Model«

• November 25th, 2008 - Edward Dennis

  Edward Dennis University of California San Diego, USA »Eicosanoid Lipidomics and Phospholipase A2 – Role in Inflammatory Disease«

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  Peter Walter University of California San Francisco, USA »Protein Homeostasis in Health and Disease«

• September 24th, 2008 - Anthony J. Pawson

  Anthony J. Pawson Samuel Lunenfeld Research Institute, Mt Sinai Hospital, Toronto, Canada »SH2 domains and tyrosine kinases - back to the future« Download CV

• March 14th, 2008 - Tim Mosmann

  Tim Mosmann Center for Vaccine Biology and Immunolgy, University of Rochester, NY, USA »Significance of T Cell Diversity in Immune Responses« Download CV

• March 03th, 2008 - Hidde Ploegh

  Hidde Ploegh Whitehead Institute for Biomedical Research, Cambridge, USA »Herpesviruses as Tools: Antigen Presentation and Protein Quality Control«

• January 22th, 2008 - Josef Penninger

  Josef Penninger Institute of Molecular Biotechnology, Vienna, Austria »From Systems Genetics in Flies to Human Medicine« Download CV

• November 27th, 2007 - Garret A. FitzGerald

  Garret A. FitzGerald Dept. of Pharmacology, University of Pennsylvania School of Medicine, USA »Therapeutic Adventures in the Arachidonic Acid Cascade« Download CV

• November 13th, 2007 - Matthias Kleiner

  Matthias Kleiner Präsident der Deutschen Forschungsgemeinschaft, Bonn, Germany »Wissenschaft im Wettbewerb«

• June 05th, 2007 - Peter Mombaerts

  Peter Mombaerts The Rockefeller University, New York and Max-Planck-Institute of Biophysics, Frankfurt, Germany »Olfaction targeted« Download CV

• March 14th, 2007 - Harry F. Noller

  Harry F. Noller Center for Molecular Biology of RNA, Sinsheimer Laboratories University of California - Santa Cruz, USA »Ribosome Structure and Dynamics: Caught in the Act«

• November 09th, 2006 - Anthony Cerami

  Anthony Cerami Warren Pharmaceuticals, Inc, Ossining, NY, USA »TNF and Erythropoietin: The Lucifer and Gabriel Cytokine« Download CV

• September 19th, 2006 - Aaron Ciechanover

  Aaron Ciechanover Israel Institute of Technology, Haifa, Israel »The Ubiquitin Proteolytic System - from a Vague Idea, through Basic Mechanisms and onto Human Diseases and Drug Targeting«

• May 23th, 2006 - Roderick MacKinnon

  Roderick MacKinnon Rockefeller University/HHMI New York, USA »Structure and Function of Potassium Channels (K+)«

• March 14th, 2006 - Craig Mello

  Craig Mello Howard Hughes Medical Institute, University of Massachusetts, Worcester, USA »RNAi and Development in C. elegans« Download CV

• January 24th, 2006 - Hans Clevers

  Hans Clevers University of Utrecht, NL »Wnt and Notch Signaling Pathways in Development and Cancer of the Gut« Download CV

• December 13th, 2005 - Chris Dobson

  Chris Dobson University of Cambridge, UK »Protein Misfolding and Human Disease«

• July 05th, 2005 - Adam Smith

  Adam Smith Nature Publishing Group »Role of Publishing at the Intersection of Academic and Industrial Science«

• April 12th, 2005 - Rudolf Jaenisch

  Rudolf Jaenisch Whitehead Institute for Biomedical Research, Cambridge, UK »Nuclear Cloning, Stem Cells and Genomic Reprogramming«

• February 08th, 2005 - Jean-Marie Lehn

  Jean-Marie Lehn University Louis Pasteur, Strasbourg »Some Contributions of Supramolecular Chemistry to Life Sciences«

• December 14th, 2004 - Kai Simons

  Kai Simons Max-Planck-Institute for Molecular Cell Biology and Genetics, Dresden, Germany »Lipid Rafts: An Organizational Principle in Cell Membranes«

• July 06th, 2004 - Klaus Rajewsky

  Klaus Rajewsky Harvard Medical School, Center for Blood Research, Boston, USA »Modeling Human Diseases in the Mouse«

• May 18th, 2004 - Joseph Schlessinger

  Joseph Schlessinger Yale University School of Medicine, New Haven CT »Cell Signaling by Tyrosine Phosphorylation: From the Bench to the Bedside«

• April 20th, 2004 - Tony Hunter

  Tony Hunter The Salk Institute for Biological Studies, La Jolla »The Many Roles of Protein Phosphorylation in Cellular Signaling«

• January 29th, 2004 - Thomas R. Cech

  Thomas R. Cech Howard Hughes Medical Institute, University of Colorado, Boulder »Interdisciplinary Science for the 21st Century: The Howard Hughes Medical Institute«

• December 09th, 2003 - Peter Carmeliet

  Peter Carmeliet Flanders Universität, Leuven (Belgien) »Genetics in Mice, Zebrafish and Humans to Unravel Angioge-nesis: Therapeutic Perspectives«

• July 08th, 2003 - Salvador MoncadaSalvador Moncada

  Salvador Moncada The Wolfson Institute for Biomedical Research, London »Nitric Oxide and Cell Respiration: Physiology and Pathophysiology«

• May 13th, 2003- Helen Blau

  Helen Blau Stanford Universität, Palo Alto »Marrow-associated Stem Cells for Brain and Brawn«

• March 14th, 2003 - Richard Lerner

  Richard Lerner Scripps Research Institute, La Jolla »Antibody Catalysis, Ozone, and Atherosclerosis: New Aspects of the Immune System«

• February 11th, 2003 - Marco Baggiolini

  Marco Baggiolini Università della Svizzera Italiana, Lugano, Switzerland »Little, Big Chemokines: From Regulation of Leukocyte Traffic to Therapy of Inflammatory Diseases«

• January 14th, 2003 - Svante Pääbo

  Svante Pääbo Max-Planck-Institut für Evolutionäre Anthropologie, Leipzig, Germany »An Ape Perspective of Human Uniqueness«

• December 03th, 2002 - Konrad Beyreuther

  Konrad Beyreuther ZMBH Heidelberg »Ageing without Alzheimer«

• October 15th, 2002 - Karl Einhäupl

  Karl Einhäupl Neurologische Klinik, Charité, Berlin Vorsitzender des Wissenschaftsrats, Germany »Hochschulmedizin: zwischen Spitzenforschung und Massenuniversität?«

• July 09th, 2002 - Robert Huber

  Robert Huber Max-Planck-Institut für Biochemie, München, Germany »Molecular Machines for Protein Degradation«

• April 23th, 2002 - Günter Blobel

  Günter Blobel Rockefeller Universität, New York, USA »Protein Targeting«